2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid - Names and Identifiers
2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid - Introduction
2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid is an organic compound with the molecular formula C7H3Cl2F2NO2 and a molecular weight of 218.01g/mol. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid is a white crystalline solid.
-Solubility: It is almost insoluble in water and soluble in organic solvents such as ethanol and chloroform.
-Melting point: 2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid has a melting point of about 100-103°C.
-Stability: It is relatively stable at room temperature, but may decompose under the action of high temperature, flame or strong oxidant.
Use:
- 2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid is an important organic synthesis intermediate, commonly used in the synthesis of drugs and pesticides and other organic compounds.
-It can also be used as a reagent for heterocyclic compounds for analysis, testing and research.
Method:
2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid is generally prepared by chemical synthesis, which can be synthesized by the following steps:
1. First, 3,5-dichloropyridine is reacted with sodium hydroxide in a solvent and under appropriate reaction conditions to generate a pyridone intermediate.
2. Then, the generated pyridone is reacted with difluoroacetyl chloride to obtain the final product 2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid.
Safety Information:
- 2-(3,5-dichloropyridin-2-yl)-2,2-difluoroacetic acid may be harmful to human body and environment, and safety operation regulations shall be strictly observed, wear appropriate protective equipment for operation.
-It may cause irritation and damage to the eyes, skin, respiratory tract and digestive system, so contact should be avoided during operation. In case of accidental contact, rinse the affected area immediately with clean water and seek medical help.
-It should be kept away from fire and oxidizing agents, and avoid contact with flammable substances to prevent fire and explosion.
-If waste is to be disposed of, it should be disposed of in accordance with local regulations to avoid pollution to the environment.
Last Update：2024-04-09 21:01:54